Key moments in Iowa State's loss to Tennessee in the Sweet 16

The Volunteers out-rebounded ISU 43-22 and dominated the offensive glass 18-6.

After a 5-for-5 start to the game at the foul line in the first half, the Cyclones went 10-for-20 in the second half. Free throws haunted the Cyclones all season — they were the No. 15 Big 12 team at 67.7%.

ISU's run this march ends without second-team All-American Joshua Jefferson. The senior forward played two-and-a-half minutes in the NCAA tournament before spraining his ankle in the first-round game against Tennessee State.

ESPN reports Joshua Jefferson is out for Tennessee game

ESPN's Pete Thamel reported Friday night ISU forward Joshua Jefferson will not play against Tennessee. 

Jefferson did not participate in ISU's pregame warmup in the tunnel outside the team's locker room. He entered the game with a questionable tag after he sprained his left ankle last Friday in ISU's first round NCAA Tournament game. 

Jefferson said he returned to walking on his ankle Wednesday. He appeared at practice in high-top basketball shoes and did some light dribbling and shooting activity. 

Big 12 Commissioner Brett Yormark is in Chicago for Iowa State's game vs Tennessee

The winner of Iowa State and Tennessee will face No. 1 seed Michigan in the Elite Eight

No. 1 seed Michigan beat No. 4 Alabama 90-77 Friday. Michigan is 34-3 this season and 19-1 in Big 10 play. 

Tennessee offensive rebounding keeps ISU lead to two

Iowa State leads 13-11 | 11:53 1H

Tennessee has grabbed seven offensive rebounds in the first eight minutes. That has kept them in touch with the Cyclones despite a 31% shooting percentage from the field. ISU is shooting 40% from the field and is 2-for-5 from 3.

Toure's Behind-the-back assist to Lipsey gives ISU a lead

Iowa State leads 33-32 | 51.2 seconds H1

Freshman ISU guard started a fastbreak and made behind-the-back bounce pass to point guard Tamin Lipsey to give ISU a 33-32 lead. Nate Heise's three-pointer on the previous Cyclone possession has added to make Cyclone fans chant "I-S-U."

Lipsey's layup crawls off, Cyclones trail at half

Tennessee leads 34-33 | HALF

ISU couldn't get a go-ahead bucket before the half like against Kentucky on Sunday. Lipsey's layup crawls off the rim and Tennessee maintains a slim lead. 

The Cyclones have shot 43% from the field and 31% from three. Tennessee is shooting 47% from the field and 18% from three.

The Volunteers have 10 offensive rebounds to Iowa State's two and are winning the total rebound margin 22-10. 

Tennessee takes largest lead of game

Tennessee leads 49-41 | 14:19 2H

A back-and-forth game has tipped in in the Volunteers' favor. Tennessee has picked up its three-point shooting in the second half (three-for-four).

Tennessee maintaining double-digit lead

Tennessee leads 61-49 | 7:48 2H

The Cyclones haven't scored a field goal in the past 4:49 of game time. Since a 5-for-5 start from the foul line in the first half, the Cyclones have gone 6-for-12, slowing momentum for a comeback. 

Joshua Jefferson listed as "questionable" for Iowa State's game vs Tennessee

What Tennessee players think of Iowa State's ball pressure and what they've done to prepare

Will Iowa State's Joshua Jefferson play vs Tennessee? Here's the latest